CANNOT SEE THE WOOD FOR THE TREES? ARNOLD VON HARFF’S PERCEPTION OF THE NATURAL WORLD ALONG THE MEDITERRANEAN ROADS (1496-1498)

Cannot See the Wood for the Trees? Arnold von Harff’s Perception of the Natural World along the Mediterranean Roads (1496-1498)

Abstract Wondering how medieval people perceived their environment has long moved scholars onto untamed research paths.A strong focus on scholastic writings as sources has left an unfinished picture of medieval societies’ perceptions of nature.Pilgrimage accounts written by lay authors offer a rare opportunity to explore other perspectives on nat

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Induction of apoptosis by apocarotenoids in B16 melanoma cells through ROS-mediated mitochondrial-dependent pathway

Bixin and norbixin are natural food colourants synthesised from Bixa orellana L seeds.This study explores the mechanism of apocarotenoids (bixin and norbixin) on the aggressive B16 murine melanoma as an anti-cancer agent.The apocarotenoids inhibited the cell viability of B16 melanoma in a time- and concentration-dependent manner.Apocarotenoids mark

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Salvia miltiorrhiza Induces Tonic Contraction of the Lower Esophageal Sphincter in Rats via Activation of Extracellular Ca2+ Influx

Up to 40% of patients with gastroesophageal reflux disease (GERD) suffer from proton pump inhibitor refractory Art Print GERD but clinically the medications to strengthen the lower esophageal sphincter (LES) to avoid irritating reflux are few in number.This study aimed to examine whether Salvia miltiorrhiza (SM) extracts induce tonic contraction of

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